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KIF13A

GENERAL INFORMATION

Gene name

 KIF13A

Gene description

 Kinesin family member 13A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA029253 , HPA029254
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 KIF13A (HGNC Symbol)

Synonyms

 bA500C11.2

Description

 Kinesin family member 13A (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

 6

Cytoband

 p22.3

Chromosome location (bp)

 17759183 - 17987623

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000137177 (version 83.38)

Entrez gene

 63971

UniProt

 Q9H1H9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H1H9

Antibodypedia

 KIF13A antibodies

PROTEIN BROWSER
KIF13A-001
KIF13A-002
KIF13A-003
KIF13A-004
KIF13A-005
KIF13A-006
KIF13A-008
KIF13A-013

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF13A-001
ENSP00000259711
ENST00000259711
Q9H1H9 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006886 [intracellular protein transport]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008333 [endosome to lysosome transport]
GO:0010008 [endosome membrane]
GO:0016887 [ATPase activity]
GO:0030496 [midbody]
GO:0032438 [melanosome organization]
GO:0032588 [trans-Golgi network membrane]
GO:0035459 [cargo loading into vesicle]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
Show all
 1805 aa
202.3 kDa 		No 0
KIF13A-002
ENSP00000368103
ENST00000378826
Q9H1H9 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006886 [intracellular protein transport]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008333 [endosome to lysosome transport]
GO:0010008 [endosome membrane]
GO:0016887 [ATPase activity]
GO:0030496 [midbody]
GO:0032438 [melanosome organization]
GO:0032588 [trans-Golgi network membrane]
GO:0035459 [cargo loading into vesicle]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
Show all
 1770 aa
198.6 kDa 		No 0
KIF13A-003
ENSP00000351150
ENST00000358380
H0Y307 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005871 [kinesin complex]
GO:0007018 [microtubule-based movement]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 889 aa
100.5 kDa 		No 0
KIF13A-004
ENSP00000368120
ENST00000378843
Q9H1H9 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006886 [intracellular protein transport]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008333 [endosome to lysosome transport]
GO:0010008 [endosome membrane]
GO:0016887 [ATPase activity]
GO:0030496 [midbody]
GO:0032438 [melanosome organization]
GO:0032588 [trans-Golgi network membrane]
GO:0035459 [cargo loading into vesicle]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
Show all
 1757 aa
197.1 kDa 		No 0
KIF13A-005
ENSP00000368091
ENST00000378814
Q9H1H9 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006886 [intracellular protein transport]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008333 [endosome to lysosome transport]
GO:0010008 [endosome membrane]
GO:0016887 [ATPase activity]
GO:0030496 [midbody]
GO:0032438 [melanosome organization]
GO:0032588 [trans-Golgi network membrane]
GO:0035459 [cargo loading into vesicle]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
Show all
 1749 aa
196.1 kDa 		No 0
KIF13A-006
ENSP00000425616
ENST00000502297
H0Y9Z7 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005871 [kinesin complex]
GO:0007018 [microtubule-based movement]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 801 aa
88.8 kDa 		No 0
KIF13A-008
ENSP00000425453
ENST00000502704
Q9H1H9 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0006886 [intracellular protein transport]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0008333 [endosome to lysosome transport]
GO:0010008 [endosome membrane]
GO:0016887 [ATPase activity]
GO:0030496 [midbody]
GO:0032438 [melanosome organization]
GO:0032588 [trans-Golgi network membrane]
GO:0035459 [cargo loading into vesicle]
GO:0043001 [Golgi to plasma membrane protein transport]
GO:0072383 [plus-end-directed vesicle transport along microtubule]
Show all
 70 aa
7.7 kDa 		No 0
KIF13A-013
ENSP00000422808
ENST00000506044
H0Y925 [Direct mapping]
Kinesin-like protein KIF13A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005871 [kinesin complex]
GO:0007018 [microtubule-based movement]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 270 aa
30.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.