Expression of SLC22A23 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 22, member 23

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA014697

GENE INFORMATION
Gene name	SLC22A23 (HGNC Symbol)
Synonyms	C6orf85, FLJ22174
Description	Solute carrier family 22, member 23 (HGNC Symbol)
Entrez gene summary	SLC22A23 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
Chromosome	6
Cytoband	p25.2
Chromosome location (bp)	3268962 - 3457022
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137266 (version 83.38)
Entrez gene	63027
UniProt	A1A5C7 (UniProt - Evidence at protein level)
neXtProt	NX_A1A5C7
Antibodypedia	SLC22A23 antibodies

PROTEIN BROWSER

SLC22A23-001	SLC22A23-002	SLC22A23-005	SLC22A23-006	SLC22A23-007	SLC22A23-009	SLC22A23-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC22A23-001 ENSP00000369653 ENST00000380298	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	361 aa 38 kDa	No	6
SLC22A23-002 ENSP00000410245 ENST00000436008	C9J4Z0 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	694 aa 74.6 kDa	No	>9
SLC22A23-005 ENSP00000419463 ENST00000490273	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	405 aa 44.8 kDa	No	8
SLC22A23-006 ENSP00000385028 ENST00000406686	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	686 aa 73.7 kDa	No	>9
SLC22A23-007 ENSP00000418134 ENST00000485307	H7C4T9 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	440 aa 48.7 kDa	No	9
SLC22A23-009 ENSP00000369657 ENST00000380302	A1A5C7 [Direct mapping] Solute carrier family 22 member 23 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0008514 [organic anion transmembrane transporter activity] GO:0015711 [organic anion transport] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0098656 [anion transmembrane transport] Show all	405 aa 44.8 kDa	No	8
SLC22A23-010 ENSP00000418985 ENST00000467177	C9IZW5 [Direct mapping] Solute carrier family 22 member 23 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0016021 [integral component of membrane] GO:0022857 [transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	386 aa 43.3 kDa	No	9