Fields »
ABOUT
HELP
BLOG
CPEB2

GENERAL INFORMATION

Gene name

 CPEB2

Gene description

 Cytoplasmic polyadenylation element binding protein 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CPEB2

Synonyms

Description

 Cytoplasmic polyadenylation element binding protein 2 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 p15.32

Chromosome location (bp)

 15002674 - 15070153

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000137449 (version 83.38)

Entrez gene

 132864

UniProt

 Q7Z5Q1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7Z5Q1

Antibodypedia

 CPEB2 antibodies

PROTEIN BROWSER
CPEB2-001
CPEB2-002
CPEB2-005
CPEB2-006
CPEB2-007
CPEB2-008
CPEB2-201
CPEB2-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CPEB2-001
ENSP00000424084
ENST00000507071
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 589 aa
64.9 kDa 		No 0
CPEB2-002
ENSP00000334058
ENST00000345451
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 559 aa
61.7 kDa 		No 0
CPEB2-005
ENSP00000371832
ENST00000382395
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 567 aa
62.7 kDa 		No 0
CPEB2-006
ENSP00000371838
ENST00000382401
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 562 aa
62.1 kDa 		No 0
CPEB2-007
ENSP00000259997
ENST00000259997
J3KN18 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
Show all
 597 aa
65.9 kDa 		No 0
CPEB2-008
ENSP00000423890
ENST00000509684
H0Y9D9 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
Show all
 167 aa
18.6 kDa 		No 0
CPEB2-201
ENSP00000414270
ENST00000442003
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 1007 aa
107 kDa 		No 0
CPEB2-202
ENSP00000443985
ENST00000538197
Q7Z5Q1 [Direct mapping]
Cytoplasmic polyadenylation element-binding protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000900 [translation repressor activity, nucleic acid binding]
GO:0003676 [nucleic acid binding]
GO:0003730 [mRNA 3'-UTR binding]
GO:0005095 [GTPase inhibitor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005844 [polysome]
GO:0006412 [translation]
GO:0008135 [translation factor activity, RNA binding]
GO:0008187 [poly-pyrimidine tract binding]
GO:0032869 [cellular response to insulin stimulus]
GO:0034260 [negative regulation of GTPase activity]
GO:0034599 [cellular response to oxidative stress]
GO:0035925 [mRNA 3'-UTR AU-rich region binding]
GO:0043005 [neuron projection]
GO:0043022 [ribosome binding]
GO:0043023 [ribosomal large subunit binding]
GO:0043024 [ribosomal small subunit binding]
GO:0044822 [poly(A) RNA binding]
GO:0045202 [synapse]
GO:0045900 [negative regulation of translational elongation]
GO:0071243 [cellular response to arsenic-containing substance]
GO:0071456 [cellular response to hypoxia]
GO:1900248 [negative regulation of cytoplasmic translational elongation]
GO:1990124 [messenger ribonucleoprotein complex]
GO:2000766 [negative regulation of cytoplasmic translation]
Show all
 1034 aa
109.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.