Expression of RNF121 in cancer - Summary - The Human Protein Atlas

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RNF121

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Ring finger protein 121

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046041

GENE INFORMATION
Gene name	RNF121 (HGNC Symbol)
Synonyms	FLJ11099
Description	Ring finger protein 121 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively spliced transcript variants have been noted for this gene, however, not all are likely to encode viable protein products. [provided by RefSeq, Sep 2008]
Chromosome	11
Cytoband	q13.4
Chromosome location (bp)	71928701 - 71997597
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137522 (version 83.38)
Entrez gene	55298
UniProt	Q9H920 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H920
Antibodypedia	RNF121 antibodies

PROTEIN BROWSER

RNF121-001	RNF121-002	RNF121-006	RNF121-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RNF121-001 ENSP00000354571 ENST00000361756	Q9H920 [Direct mapping] RING finger protein 121 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0061630 [ubiquitin protein ligase activity] Show all	327 aa 37.9 kDa	No	6
RNF121-002 ENSP00000377316 ENST00000393713	C9JQY5 [Direct mapping] RING finger protein 121 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0061630 [ubiquitin protein ligase activity] Show all	205 aa 23.8 kDa	No	4
RNF121-006 ENSP00000431286 ENST00000530137	G3V148 [Direct mapping] RING finger protein 121; Ring finger protein 121, isoform CRA_c Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0061630 [ubiquitin protein ligase activity] Show all	295 aa 34.5 kDa	No	6
RNF121-009 ENSP00000433574 ENST00000533380	E9PKE9 [Direct mapping] RING finger protein 121 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0016567 [protein ubiquitination] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0061630 [ubiquitin protein ligase activity] Show all	167 aa 19.5 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.