Cell atlas - BTG4 - The Human Protein Atlas

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BTG4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Endoplasmic reticulum
	Golgi apparatus

Human cell
	Endoplasmic Reticulum
	Golgi Apparatus

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GENERAL INFORMATION
Gene name	BTG4
Gene description	B-cell translocation gene 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the endoplasmic reticulum & the Golgi apparatus.
RNA cell category	Cell line enhanced (Karpas-707, CACO-2, U-266/70)
Protein evidence	Evidence at transcript level
Main location	Localized to the Endoplasmic reticulum (approved), Golgi apparatus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA057157
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (Karpas-707, CACO-2, U-266/70) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the endoplasmic reticulum & the Golgi apparatus.

Main location

Endoplasmic reticulum (approved), Golgi apparatus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA057157	CACO-2	Endoplasmic reticulum
	HPA057157	CACO-2	Golgi apparatus
	HPA057157	U-2 OS	No staining

GENE INFORMATION
Gene name	BTG4 (HGNC Symbol)
Synonyms	PC3B
Description	B-cell translocation gene 4 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q23.1
Chromosome location (bp)	111467526 - 111512354
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000137707 (version 83.38)
Entrez gene	54766
UniProt	Q9NY30 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NY30
Antibodypedia	BTG4 antibodies

PROTEIN BROWSER

BTG4-001	BTG4-002	BTG4-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTG4-001 ENSP00000348300 ENST00000356018	Q9NY30 [Direct mapping] Protein BTG4 Show all	Predicted intracellular proteins Show all	GO:0005575 [cellular_component] GO:0007050 [cell cycle arrest] GO:0008285 [negative regulation of cell proliferation] GO:0030182 [neuron differentiation] GO:0045930 [negative regulation of mitotic cell cycle] Show all	223 aa 26 kDa	No	0
BTG4-002 ENSP00000432018 ENST00000525791	Q9NY30 [Direct mapping] Protein BTG4 Show all	Predicted intracellular proteins Show all	GO:0005575 [cellular_component] GO:0007050 [cell cycle arrest] GO:0008285 [negative regulation of cell proliferation] GO:0030182 [neuron differentiation] Show all	206 aa 24 kDa	No	0
BTG4-003 ENSP00000392358 ENST00000456861	E9PRM5 [Direct mapping] Protein BTG4 Show all	Predicted intracellular proteins Show all		160 aa 18.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.