Expression of PARP6 in cancer - Summary

CANCER ATLAS

Gene description

Poly (ADP-ribose) polymerase family, member 6

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA026991

GENE INFORMATION
Gene name	PARP6 (HGNC Symbol)
Synonyms	pART17
Description	Poly (ADP-ribose) polymerase family, member 6 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q23
Chromosome location (bp)	72241181 - 72272999
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137817 (version 83.38)
Entrez gene	56965
UniProt	Q2NL67 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2NL67
Antibodypedia	PARP6 antibodies

PROTEIN BROWSER

PARP6-001	PARP6-008	PARP6-010	PARP6-011	PARP6-019	PARP6-023	PARP6-201	PARP6-202	PARP6-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PARP6-001 ENSP00000456348 ENST00000569795	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 A0A024R5Z4 [Target identity:100%; Query identity:100%] Poly (ADP-ribose) polymerase family, member 6, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	630 aa 71.1 kDa	No	0
PARP6-008 ENSP00000455815 ENST00000567974	H3BQK2 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	564 aa 63.8 kDa	No	0
PARP6-010 ENSP00000403265 ENST00000419739	F5H3B4 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	553 aa 62.3 kDa	No	0
PARP6-011 ENSP00000457862 ENST00000568360	H3BUY2 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		73 aa 8.3 kDa	No	0
PARP6-019 ENSP00000457187 ENST00000566844	H3BTI3 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		26 aa 3 kDa	No	0
PARP6-023 ENSP00000456749 ENST00000569173	H3BSK7 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		80 aa 8.9 kDa	No	0
PARP6-201 ENSP00000260376 ENST00000260376	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 J7MDH3 [Target identity:100%; Query identity:100%] PARP-6-B1 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	518 aa 58.5 kDa	No	0
PARP6-202 ENSP00000287196 ENST00000287196	Q2NL67 [Direct mapping] Poly [ADP-ribose] polymerase 6 A0A024R5Z4 [Target identity:100%; Query identity:100%] Poly (ADP-ribose) polymerase family, member 6, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	630 aa 71.1 kDa	No	0
PARP6-203 ENSP00000484561 ENST00000616176	A0A087X1Y8 [Direct mapping] Poly [ADP-ribose] polymerase 6 Show all	Predicted intracellular proteins Show all		440 aa 49.6 kDa	No	0