Cell atlas - ZNF280D - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ZNF280D
Gene description	Zinc finger protein 280D
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & nucleoplasm. In addition localized to the Golgi apparatus & centrosome.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Cytosol (approved)
Additional location	In addition localized to the Golgi apparatus (approved), Centrosome (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA030233
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & nucleoplasm. In addition localized to the Golgi apparatus & centrosome.

Main location

Nucleoplasm (approved), Cytosol (approved)

Additional location

Golgi apparatus (approved), Centrosome (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA030233	A-431	Nucleoplasm
		Centrosome
		Cytosol
HPA030233	U-2 OS	Nucleoplasm
		Golgi apparatus
		Cytosol
HPA030233	U-251 MG	Nucleoplasm
		Centrosome
		Cytosol

GENE INFORMATION
Gene name	ZNF280D (HGNC Symbol)
Synonyms	FLJ20086, SUHW4, ZNF634
Description	Zinc finger protein 280D (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q21.3
Chromosome location (bp)	56630181 - 56918571
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137871 (version 83.38)
Entrez gene	54816
UniProt	Q6N043 (UniProt - Evidence at protein level)
neXtProt	NX_Q6N043
Antibodypedia	ZNF280D antibodies

PROTEIN BROWSER

ZNF280D-001	ZNF280D-002	ZNF280D-003	ZNF280D-007	ZNF280D-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF280D-001 ENSP00000454111 ENST00000559237	Q6N043 [Direct mapping] Zinc finger protein 280D Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	966 aa 107.9 kDa	No	0
ZNF280D-002 ENSP00000453706 ENST00000558320	Q6N043 [Direct mapping] Zinc finger protein 280D Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	158 aa 17.1 kDa	No	0
ZNF280D-003 ENSP00000267807 ENST00000267807	Q6N043 [Direct mapping] Zinc finger protein 280D Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	979 aa 109.3 kDa	No	0
ZNF280D-007 ENSP00000453045 ENST00000559000	H0YL38 [Direct mapping] Zinc finger protein 280D Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	747 aa 84.1 kDa	No	0
ZNF280D-014 ENSP00000453912 ENST00000559352	H0YN90 [Direct mapping] Zinc finger protein 280D Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	80 aa 9 kDa	No	0