Expression of CGREF1 in cancer - Summary

CANCER ATLAS

Gene description

Cell growth regulator with EF-hand domain 1

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA008241

GENE INFORMATION
Gene name	CGREF1 (HGNC Symbol)
Synonyms	CGR11
Description	Cell growth regulator with EF-hand domain 1 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	27098889 - 27119115
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138028 (version 83.38)
Entrez gene	10669
UniProt	Q99674 (UniProt - Evidence at transcript level)
neXtProt	NX_Q99674
Antibodypedia	CGREF1 antibodies

PROTEIN BROWSER

CGREF1-001	CGREF1-003	CGREF1-004	CGREF1-005	CGREF1-006	CGREF1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CGREF1-001 ENSP00000385452 ENST00000402394	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] GO:0030308 [negative regulation of cell growth] Show all	318 aa 33.5 kDa	Yes	0
CGREF1-003 ENSP00000385103 ENST00000402550	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] Show all	132 aa 14.3 kDa	Yes	0
CGREF1-004 ENSP00000386113 ENST00000405600	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] Show all	318 aa 33.5 kDa	Yes	0
CGREF1-005 ENSP00000324025 ENST00000312734	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] Show all	318 aa 33.5 kDa	Yes	0
CGREF1-006 ENSP00000385574 ENST00000404694	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] Show all	440 aa 47.1 kDa	No	0
CGREF1-201 ENSP00000260595 ENST00000260595	Q99674 [Direct mapping] Cell growth regulator with EF hand domain protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005576 [extracellular region] GO:0006950 [response to stress] GO:0007050 [cell cycle arrest] GO:0007155 [cell adhesion] GO:0008285 [negative regulation of cell proliferation] Show all	301 aa 31.9 kDa	Yes	0