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EMILIN1

GENERAL INFORMATION

Gene name

 EMILIN1

Gene description

 Elastin microfibril interfacer 1

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Selective expression in connective tissue and distinct positivity in extracellular matrix in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.

Reliability score

 Supported based on 1 antibody.
HPA002822
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 EMILIN1 (HGNC Symbol)

Synonyms

 DKFZp586M121, gp115

Description

 Elastin microfibril interfacer 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009]

Chromosome

 2

Cytoband

 p23.3

Chromosome location (bp)

 27078567 - 27086408

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000138080 (version 83.38)

Entrez gene

 11117

UniProt

neXtProt

Antibodypedia

 EMILIN1 antibodies

PROTEIN BROWSER
EMILIN1-001
EMILIN1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EMILIN1-001
ENSP00000369677
ENST00000380320
A0A0C4DFX3 [Direct mapping]
EMILIN-1
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005578 [proteinaceous extracellular matrix]
GO:0005581 [collagen trimer]
GO:0010811 [positive regulation of cell-substrate adhesion]
GO:0030023 [extracellular matrix constituent conferring elasticity]
GO:0030198 [extracellular matrix organization]
GO:0042802 [identical protein binding]
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 1016 aa
106.7 kDa 		Yes 0
EMILIN1-002
ENSP00000411201
ENST00000433140
A0A0A0MT20 [Direct mapping]
EMILIN-1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005581 [collagen trimer]
Show all
 347 aa
35.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.