Expression of LBX1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Ladybird homeobox 1

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Glioma

STAINING SUMMARY

HPA002086

GENE INFORMATION
Gene name	LBX1 (HGNC Symbol)
Synonyms	HPX6, LBX1H
Description	Ladybird homeobox 1 (HGNC Symbol)
Entrez gene summary	This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q24.32
Chromosome location (bp)	101226195 - 101229794
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000138136 (version 83.38)
Entrez gene	10660
UniProt	P52954 (UniProt - Evidence at transcript level)
neXtProt	NX_P52954
Antibodypedia	LBX1 antibodies

PROTEIN BROWSER

LBX1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LBX1-001 ENSP00000359212 ENST00000370193	P52954 [Direct mapping] Transcription factor LBX1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0001947 [heart looping] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007517 [muscle organ development] GO:0008285 [negative regulation of cell proliferation] GO:0009653 [anatomical structure morphogenesis] GO:0021522 [spinal cord motor neuron differentiation] GO:0021920 [regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification] GO:0043565 [sequence-specific DNA binding] GO:0045665 [negative regulation of neuron differentiation] GO:0048663 [neuron fate commitment] GO:0048664 [neuron fate determination] Show all	281 aa 30.2 kDa	No	0