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MDH1B

GENERAL INFORMATION

Gene name

 MDH1B

Gene description

 Malate dehydrogenase 1B, NAD (soluble)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (testis, fallopian tube)
GTEx:Tissue enhanced (testis)
FANTOM5:Tissue enhanced (testis, pituitary gland)

Protein evidence

 Evidence at transcript level

Protein expression

 RNA data suggests expression in selected group of tissues, most abundant in testis.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 1 antibody.
HPA034741
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (testis, fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, pituitary gland)

GENE INFORMATION

Gene name

 MDH1B (HGNC Symbol)

Synonyms

 FLJ25341, RP11-95H11

Description

 Malate dehydrogenase 1B, NAD (soluble) (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q33.3

Chromosome location (bp)

 206737763 - 206765547

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000138400 (version 83.38)

Entrez gene

 130752

UniProt

 Q5I0G3 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5I0G3

Antibodypedia

 MDH1B antibodies

PROTEIN BROWSER
MDH1B-001
MDH1B-005
MDH1B-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MDH1B-001
ENSP00000363533
ENST00000374412
Q5I0G3 [Direct mapping]
Putative malate dehydrogenase 1B
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003824 [catalytic activity]
GO:0005975 [carbohydrate metabolic process]
GO:0006099 [tricarboxylic acid cycle]
GO:0006108 [malate metabolic process]
GO:0016615 [malate dehydrogenase activity]
GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor]
GO:0055114 [oxidation-reduction process]
Show all
 518 aa
58.6 kDa 		No 0
MDH1B-005
ENSP00000416577
ENST00000449792
C9JER5 [Direct mapping]
Putative malate dehydrogenase 1B
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003824 [catalytic activity]
GO:0005975 [carbohydrate metabolic process]
GO:0006108 [malate metabolic process]
GO:0016615 [malate dehydrogenase activity]
GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor]
GO:0055114 [oxidation-reduction process]
Show all
 420 aa
47.1 kDa 		No 0
MDH1B-006
ENSP00000389916
ENST00000454776
Q5I0G3 [Direct mapping]
Putative malate dehydrogenase 1B
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0003824 [catalytic activity]
GO:0005975 [carbohydrate metabolic process]
GO:0006099 [tricarboxylic acid cycle]
GO:0006108 [malate metabolic process]
GO:0016615 [malate dehydrogenase activity]
GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor]
GO:0055114 [oxidation-reduction process]
Show all
 517 aa
58.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.