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SEC31 homolog A, COPII coat complex component (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
O94979 [Direct mapping] Protein transport protein Sec31A A0A024RDD3 [Target identity:100%; Query identity:100%] SEC31-like 1 (S. cerevisiae), isoform CRA_d
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Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A A0A024RDH6 [Target identity:100%; Query identity:100%] SEC31-like 1 (S. cerevisiae), isoform CRA_b
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Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A A0A024RDD3 [Target identity:100%; Query identity:100%] SEC31-like 1 (S. cerevisiae), isoform CRA_d
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
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Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]
O94979 [Direct mapping] Protein transport protein Sec31A A0A024RDD3 [Target identity:100%; Query identity:100%] SEC31-like 1 (S. cerevisiae), isoform CRA_d
Show all
Transporters Primary Active Transporters Predicted intracellular proteins Plasma proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane] GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0005829 [cytosol] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0012507 [ER to Golgi transport vesicle membrane] GO:0015031 [protein transport] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0030120 [vesicle coat] GO:0030127 [COPII vesicle coat] GO:0030134 [ER to Golgi transport vesicle] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0043231 [intracellular membrane-bounded organelle] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048208 [COPII vesicle coating] GO:0048306 [calcium-dependent protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0051592 [response to calcium ion] GO:0061024 [membrane organization] GO:0070971 [endoplasmic reticulum exit site]