Tissue expression of SEPT11 - Summary - The Human Protein Atlas

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SEPT11

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SEPT11
Gene description	Septin 11
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA003459 , HPA005665
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

N/A

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SEPT11 (HGNC Symbol)
Synonyms	FLJ10849
Description	Septin 11 (HGNC Symbol)
Entrez gene summary	SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009]
Chromosome	4
Cytoband	q21.1
Chromosome location (bp)	76949703 - 77040384
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138758 (version 83.38)
Entrez gene	55752
UniProt	Q9NVA2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NVA2
Antibodypedia	SEPT11 antibodies

PROTEIN BROWSER

SEPT11-001	SEPT11-002	SEPT11-004	SEPT11-005	SEPT11-006	SEPT11-008	SEPT11-009	SEPT11-012	SEPT11-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEPT11-001 ENSP00000264893 ENST00000264893	Q9NVA2 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0007049 [cell cycle] GO:0030054 [cell junction] GO:0030424 [axon] GO:0043197 [dendritic spine] GO:0051291 [protein heterooligomerization] GO:0051301 [cell division] GO:0070062 [extracellular exosome] Show all	429 aa 49.4 kDa	No	0
SEPT11-002 ENSP00000424925 ENST00000505788	D6RER5 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	432 aa 49.8 kDa	No	0
SEPT11-004 ENSP00000422896 ENST00000510515	Q9NVA2 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0001725 [stress fiber] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005737 [cytoplasm] GO:0007049 [cell cycle] GO:0030054 [cell junction] GO:0030424 [axon] GO:0043197 [dendritic spine] GO:0051291 [protein heterooligomerization] GO:0051301 [cell division] GO:0070062 [extracellular exosome] Show all	439 aa 50.8 kDa	No	0
SEPT11-005 ENSP00000420839 ENST00000510641	D6RDU5 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	372 aa 43.1 kDa	No	0
SEPT11-006 ENSP00000426344 ENST00000502584	D6RGI3 [Direct mapping] Septin 11, isoform CRA_b; Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	425 aa 49 kDa	No	0
SEPT11-008 ENSP00000425262 ENST00000504637	D6RDP1 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	126 aa 14.1 kDa	No	0
SEPT11-009 ENSP00000422047 ENST00000512778	D6R9Y6 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	136 aa 15.3 kDa	No	0
SEPT11-012 ENSP00000424122 ENST00000502401	H0Y9G8 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	82 aa 9.8 kDa	No	0
SEPT11-015 ENSP00000423103 ENST00000506731	H0Y961 [Direct mapping] Septin-11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005525 [GTP binding] Show all	160 aa 19.3 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.