Expression of B4GALNT3 in cancer - Summary

CANCER ATLAS

Gene description

Beta-1,4-N-acetyl-galactosaminyl transferase 3

Protein class

Enzymes, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA011404

GENE INFORMATION
Gene name	B4GALNT3 (HGNC Symbol)
Synonyms	B4GalNac-T3, FLJ16224, FLJ40362
Description	Beta-1,4-N-acetyl-galactosaminyl transferase 3 (HGNC Symbol)
Entrez gene summary	B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]
Chromosome	12
Cytoband	p13.33
Chromosome location (bp)	460364 - 563509
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139044 (version 83.38)
Entrez gene	283358
UniProt	Q6L9W6 (UniProt - Evidence at protein level)
neXtProt	NX_Q6L9W6
Antibodypedia	B4GALNT3 antibodies

PROTEIN BROWSER

B4GALNT3-001	B4GALNT3-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B4GALNT3-001 ENSP00000266383 ENST00000266383	Q6L9W6 [Direct mapping] Beta-1,4-N-acetylgalactosaminyltransferase 3 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0008152 [metabolic process] GO:0008376 [acetylgalactosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0032580 [Golgi cisterna membrane] GO:0033842 [N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity] Show all	998 aa 115 kDa	Yes	0
B4GALNT3-008 ENSP00000322953 ENST00000322843	E9PHD9 [Direct mapping] Beta-1,4-N-acetylgalactosaminyltransferase 3 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all		637 aa 73.2 kDa	No	0