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Most of the cancer tissues showed weak to moderate cytoplasmic positivity. Additional nuclear or membranous immunoreactivity was observed in a few cases. Gliomas, lymphomas and carcinoids as well as skin cancers were in general negative.
GENE INFORMATION
Gene name
CPNE8
Synonyms
Description
Copine VIII (HGNC Symbol)
Entrez gene summary
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]