Expression of C1RL in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Complement component 1, r subcomponent-like

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA011338	CAB026172

GENE INFORMATION
Gene name	C1RL (HGNC Symbol)
Synonyms	C1r-LP, C1RL1
Description	Complement component 1, r subcomponent-like (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	7089587 - 7109273
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139178 (version 83.38)
Entrez gene	51279
UniProt	Q9NZP8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZP8
Antibodypedia	C1RL antibodies

PROTEIN BROWSER

C1RL-001	C1RL-002	C1RL-003	C1RL-005	C1RL-006	C1RL-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C1RL-001 ENSP00000266542 ENST00000266542	Q9NZP8 [Direct mapping] Complement C1r subcomponent-like protein Show all	Enzymes Peptidases Serine-type peptidases SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0006508 [proteolysis] GO:0006958 [complement activation, classical pathway] GO:0045087 [innate immune response] GO:0070062 [extracellular exosome] Show all	487 aa 53.5 kDa	Yes	0
C1RL-002 ENSP00000442611 ENST00000545337	F5H7C8 [Direct mapping] Complement C1r subcomponent-like protein Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		187 aa 20.4 kDa	Yes	0
C1RL-003 ENSP00000441885 ENST00000544702	F5GWF3 [Direct mapping] Complement C1r subcomponent-like protein Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		314 aa 33.7 kDa	Yes	0
C1RL-005 ENSP00000437398 ENST00000543933	F5H6S5 [Direct mapping] Complement C1r subcomponent-like protein Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		192 aa 21 kDa	Yes	0
C1RL-006 ENSP00000438286 ENST00000545280	F5H2Z5 [Direct mapping] Complement C1r subcomponent-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 11.7 kDa	No	0
C1RL-008 ENSP00000439180 ENST00000534950	H0YFL7 [Direct mapping] Complement C1r subcomponent-like protein Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0006508 [proteolysis] Show all	194 aa 21 kDa	No	0