Expression of NDUFA9 in cancer - Summary

CANCER ATLAS

Gene description

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa

Protein class

Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042268

GENE INFORMATION
Gene name	NDUFA9 (HGNC Symbol)
Synonyms	CI-39k, NDUFS2L, SDR22E1
Description	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa (HGNC Symbol)
Entrez gene summary	The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. A pseudogene has been identified on chromosome 12. [provided by RefSeq, May 2010]
Chromosome	12
Cytoband	p13.32
Chromosome location (bp)	4649095 - 4694317
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139180 (version 83.38)
Entrez gene	4704
UniProt	Q16795 (UniProt - Evidence at protein level)
neXtProt	NX_Q16795
Antibodypedia	NDUFA9 antibodies

PROTEIN BROWSER

NDUFA9-001	NDUFA9-006	NDUFA9-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NDUFA9-001 ENSP00000266544 ENST00000266544	Q16795 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0003954 [NADH dehydrogenase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005747 [mitochondrial respiratory chain complex I] GO:0005759 [mitochondrial matrix] GO:0006120 [mitochondrial electron transport, NADH to ubiquinone] GO:0006814 [sodium ion transport] GO:0008137 [NADH dehydrogenase (ubiquinone) activity] GO:0022904 [respiratory electron transport chain] GO:0031966 [mitochondrial membrane] GO:0032403 [protein complex binding] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] GO:0050662 [coenzyme binding] GO:1901006 [ubiquinone-6 biosynthetic process] Show all	377 aa 42.5 kDa	No	0
NDUFA9-006 ENSP00000440305 ENST00000535050	F5GY40 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003854 [3-beta-hydroxy-delta5-steroid dehydrogenase activity] GO:0006694 [steroid biosynthetic process] GO:0016616 [oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor] GO:0055114 [oxidation-reduction process] GO:1901006 [ubiquinone-6 biosynthetic process] Show all	149 aa 16.7 kDa	No	1
NDUFA9-008 ENSP00000439818 ENST00000540688	F5H0J3 [Direct mapping] NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:1901006 [ubiquinone-6 biosynthetic process] Show all	136 aa 15.7 kDa	No	0