Expression of TAPBPL in cancer - Summary

CANCER ATLAS

Gene description

TAP binding protein-like

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039545

GENE INFORMATION
Gene name	TAPBPL (HGNC Symbol)
Synonyms	FLJ10143, TAPBP-R, TAPBPR
Description	TAP binding protein-like (HGNC Symbol)
Entrez gene summary	Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008]
Chromosome	12
Cytoband	p13.31
Chromosome location (bp)	6451690 - 6466517
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139192 (version 83.38)
Entrez gene	55080
UniProt	Q9BX59 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BX59
Antibodypedia	TAPBPL antibodies

PROTEIN BROWSER

TAPBPL-001	TAPBPL-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TAPBPL-001 ENSP00000266556 ENST00000266556	Q9BX59 [Direct mapping] Tapasin-related protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0002376 [immune system process] GO:0002590 [negative regulation of antigen processing and presentation of peptide antigen via MHC class I] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0032403 [protein complex binding] Show all	468 aa 50.2 kDa	Yes	1
TAPBPL-005 ENSP00000445341 ENST00000544021	G3V1T3 [Direct mapping] TAP binding protein-like, isoform CRA_c; Tapasin-related protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		185 aa 20 kDa	Yes	0