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AMIGO2

CANCER ATLAS

Gene description

 Adhesion molecule with Ig-like domain 2

Protein class

 Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA054004

GENE INFORMATION

Gene name

 AMIGO2 (HGNC Symbol)

Synonyms

 ALI1, DEGA

Description

 Adhesion molecule with Ig-like domain 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q13.11

Chromosome location (bp)

 47075707 - 47079951

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000139211 (version 83.38)

Entrez gene

 347902

UniProt

 Q86SJ2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86SJ2

Antibodypedia

 AMIGO2 antibodies

PROTEIN BROWSER
AMIGO2-001
AMIGO2-002
AMIGO2-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AMIGO2-001
ENSP00000406020
ENST00000429635
Q86SJ2 [Direct mapping]
Amphoterin-induced protein 2
A0A024R127 [Target identity:100%; Query identity:100%]
Adhesion molecule with Ig-like domain 2, isoform CRA_a
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005886 [plasma membrane]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0007420 [brain development]
GO:0016021 [integral component of membrane]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0098609 [cell-cell adhesion]
Show all
 522 aa
57.9 kDa 		No 1
AMIGO2-002
ENSP00000449034
ENST00000550413
Q86SJ2 [Direct mapping]
Amphoterin-induced protein 2
A0A024R127 [Target identity:100%; Query identity:100%]
Adhesion molecule with Ig-like domain 2, isoform CRA_a
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005886 [plasma membrane]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0007420 [brain development]
GO:0016021 [integral component of membrane]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0098609 [cell-cell adhesion]
Show all
 522 aa
57.9 kDa 		No 1
AMIGO2-003
ENSP00000266581
ENST00000266581
Q86SJ2 [Direct mapping]
Amphoterin-induced protein 2
A0A024R127 [Target identity:100%; Query identity:100%]
Adhesion molecule with Ig-like domain 2, isoform CRA_a
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005886 [plasma membrane]
GO:0007156 [homophilic cell adhesion via plasma membrane adhesion molecules]
GO:0007157 [heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules]
GO:0007420 [brain development]
GO:0016021 [integral component of membrane]
GO:0043066 [negative regulation of apoptotic process]
GO:0043069 [negative regulation of programmed cell death]
GO:0051965 [positive regulation of synapse assembly]
GO:0098609 [cell-cell adhesion]
Show all
 522 aa
57.9 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.