Expression of PELI2 in cancer - Summary

CANCER ATLAS

Gene description

Pellino E3 ubiquitin protein ligase family member 2

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA053182

GENE INFORMATION
Gene name	PELI2
Synonyms
Description	Pellino E3 ubiquitin protein ligase family member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q22.3
Chromosome location (bp)	56117814 - 56301526
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000139946 (version 83.38)
Entrez gene	57161
UniProt	Q9HAT8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HAT8
Antibodypedia	PELI2 antibodies

PROTEIN BROWSER

PELI2-001	PELI2-002	PELI2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PELI2-001 ENSP00000267460 ENST00000267460	Q9HAT8 [Direct mapping] E3 ubiquitin-protein ligase pellino homolog 2 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001934 [positive regulation of protein phosphorylation] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0008063 [Toll signaling pathway] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling] GO:0043410 [positive regulation of MAPK cascade] GO:0045087 [innate immune response] Show all	420 aa 46.4 kDa	No	0
PELI2-002 ENSP00000452666 ENST00000559044	H0YK56 [Direct mapping] E3 ubiquitin-protein ligase pellino homolog 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008063 [Toll signaling pathway] Show all	95 aa 10.4 kDa	No	0
PELI2-003 ENSP00000453988 ENST00000561019	H0YNF4 [Direct mapping] E3 ubiquitin-protein ligase pellino homolog 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008063 [Toll signaling pathway] Show all	78 aa 8.7 kDa	No	0