Cell atlas - BNIP2 - The Human Protein Atlas

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BNIP2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	BNIP2
Gene description	BCL2/adenovirus E1B 19kDa interacting protein 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	BNIP2 (HGNC Symbol)
Synonyms	BNIP-2, Nip2
Description	BCL2/adenovirus E1B 19kDa interacting protein 2 (HGNC Symbol)
Entrez gene summary	This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. [provided by RefSeq, Mar 2011]
Chromosome	15
Cytoband	q22.2
Chromosome location (bp)	59659146 - 59689534
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000140299 (version 83.38)
Entrez gene	663
UniProt	Q12982 (UniProt - Evidence at protein level)
neXtProt	NX_Q12982
Antibodypedia	BNIP2 antibodies

PROTEIN BROWSER

BNIP2-001	BNIP2-006	BNIP2-008	BNIP2-012	BNIP2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BNIP2-001 ENSP00000267859 ENST00000267859	J3KN59 [Direct mapping] BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001824 [blastocyst development] GO:0005814 [centriole] GO:0005829 [cytosol] GO:0031616 [spindle pole centrosome] GO:0042802 [identical protein binding] GO:0043410 [positive regulation of MAPK cascade] GO:0045666 [positive regulation of neuron differentiation] GO:0051057 [positive regulation of small GTPase mediated signal transduction] GO:0051146 [striated muscle cell differentiation] GO:0051297 [centrosome organization] Show all	435 aa 48.8 kDa	No	0
BNIP2-006 ENSP00000393644 ENST00000439052	H7C096 [Direct mapping] BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005829 [cytosol] GO:0016021 [integral component of membrane] GO:0042802 [identical protein binding] Show all	204 aa 24.2 kDa	No	1
BNIP2-008 ENSP00000412767 ENST00000415213	Q12982 [Direct mapping] BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0042692 [muscle cell differentiation] GO:0042802 [identical protein binding] GO:0043066 [negative regulation of apoptotic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043547 [positive regulation of GTPase activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051149 [positive regulation of muscle cell differentiation] Show all	376 aa 43.1 kDa	No	0
BNIP2-012 ENSP00000475320 ENST00000607373	Q12982 [Direct mapping] BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005096 [GTPase activator activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005635 [nuclear envelope] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0042692 [muscle cell differentiation] GO:0042802 [identical protein binding] GO:0043066 [negative regulation of apoptotic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043547 [positive regulation of GTPase activity] GO:0048471 [perinuclear region of cytoplasm] GO:0051149 [positive regulation of muscle cell differentiation] Show all	314 aa 36 kDa	No	0
BNIP2-201 ENSP00000479818 ENST00000612191	J3KN59 [Direct mapping] BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005829 [cytosol] GO:0042802 [identical protein binding] Show all	435 aa 48.8 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.