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CDAN1

GENERAL INFORMATION

Gene name

 CDAN1

Gene description

 Codanin 1

Protein class

 Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic and membrane expression most abundant in glandular tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA039404 , HPA040787
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CDAN1 (HGNC Symbol)

Synonyms

 CDA-I, CDAI

Description

 Codanin 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]

Chromosome

 15

Cytoband

 q15.2

Chromosome location (bp)

 42723559 - 42737126

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140326 (version 83.38)

Entrez gene

 146059

UniProt

 Q8IWY9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IWY9

Antibodypedia

 CDAN1 antibodies

PROTEIN BROWSER
CDAN1-001
CDAN1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDAN1-001
ENSP00000348564
ENST00000356231
Q8IWY9 [Direct mapping]
Codanin-1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0006325 [chromatin organization]
GO:0008104 [protein localization]
GO:0008156 [negative regulation of DNA replication]
GO:0012505 [endomembrane system]
GO:0016021 [integral component of membrane]
GO:0031497 [chromatin assembly]
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 1227 aa
134.1 kDa 		No 4
CDAN1-005
ENSP00000455536
ENST00000563260
H3BPZ6 [Direct mapping]
Codanin-1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 95 aa
10 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.