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ARHGAP17

CANCER ATLAS

Gene description

 Rho GTPase activating protein 17

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA041703

GENE INFORMATION

Gene name

 ARHGAP17 (HGNC Symbol)

Synonyms

 FLJ10308, FLJ13219, NADRIN, RICH1, WBP15

Description

 Rho GTPase activating protein 17 (HGNC Symbol)

Entrez gene summary

 RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]

Chromosome

 16

Cytoband

 p12.1

Chromosome location (bp)

 24919385 - 25015666

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140750 (version 83.38)

Entrez gene

 55114

UniProt

 Q68EM7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q68EM7

Antibodypedia

 ARHGAP17 antibodies

PROTEIN BROWSER
ARHGAP17-001
ARHGAP17-002
ARHGAP17-006
ARHGAP17-007
ARHGAP17-013
ARHGAP17-014
ARHGAP17-023

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGAP17-001
ENSP00000289968
ENST00000289968
Q68EM7 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 881 aa
95.4 kDa 		No 0
ARHGAP17-002
ENSP00000303130
ENST00000303665
Q68EM7 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005923 [bicellular tight junction]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0017124 [SH3 domain binding]
GO:0043547 [positive regulation of GTPase activity]
GO:0051056 [regulation of small GTPase mediated signal transduction]
Show all
 803 aa
87.6 kDa 		No 0
ARHGAP17-006
ENSP00000460600
ENST00000571406
I3L3P1 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 95 aa
9.4 kDa 		No 0
ARHGAP17-007
ENSP00000461639
ENST00000571843
I3L4Y5 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 128 aa
13 kDa 		No 0
ARHGAP17-013
ENSP00000461426
ENST00000573449
I3L4P6 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
Show all
 76 aa
8.6 kDa 		No 0
ARHGAP17-014
ENSP00000406701
ENST00000455311
C9IZD3 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
Show all
 211 aa
24 kDa 		No 0
ARHGAP17-023
ENSP00000460985
ENST00000573765
I3L460 [Direct mapping]
Rho GTPase-activating protein 17
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 235 aa
24 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.