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KIFC3

GENERAL INFORMATION

Gene name

 KIFC3

Gene description

 Kinesin family member C3

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 24
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a few tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA021240
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 KIFC3

Synonyms

Description

 Kinesin family member C3 (HGNC Symbol)

Entrez gene summary

 KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM, Mar 2009]

Chromosome

 16

Cytoband

 q21

Chromosome location (bp)

 57758217 - 57863053

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000140859 (version 83.38)

Entrez gene

 3801

UniProt

 Q9BVG8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BVG8

Antibodypedia

 KIFC3 antibodies

PROTEIN BROWSER
«
KIFC3-001
KIFC3-002
KIFC3-003
KIFC3-004
KIFC3-006
KIFC3-007
KIFC3-009
KIFC3-010
KIFC3-011
KIFC3-013
KIFC3-014
KIFC3-017
KIFC3-018
KIFC3-020
KIFC3-021
KIFC3-023
KIFC3-025
KIFC3-026
KIFC3-027
KIFC3-028
KIFC3-030
KIFC3-031
KIFC3-033
KIFC3-034
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIFC3-001
ENSP00000368976
ENST00000379655
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005794 [Golgi apparatus]
GO:0005813 [centrosome]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007017 [microtubule-based process]
GO:0007018 [microtubule-based movement]
GO:0007030 [Golgi organization]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 833 aa
92.8 kDa 		No 0
KIFC3-002
ENSP00000454659
ENST00000465878
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007018 [microtubule-based movement]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 687 aa
77.1 kDa 		No 0
KIFC3-003
ENSP00000401696
ENST00000445690
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007018 [microtubule-based movement]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 826 aa
92 kDa 		No 0
KIFC3-004
ENSP00000444012
ENST00000543930
B7Z896 [Direct mapping]
Kinesin-like protein
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 684 aa
76.7 kDa 		No 0
KIFC3-006
ENSP00000456239
ENST00000562903
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007018 [microtubule-based movement]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 687 aa
77.1 kDa 		No 0
KIFC3-007
ENSP00000438805
ENST00000540079
F5H3M2 [Direct mapping]
Kinesin-like protein
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 724 aa
81.4 kDa 		No 0
KIFC3-009
ENSP00000442008
ENST00000541240
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007018 [microtubule-based movement]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 848 aa
94.3 kDa 		No 0
KIFC3-010
ENSP00000396399
ENST00000421376
Q9BVG8 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005813 [centrosome]
GO:0005874 [microtubule]
GO:0005915 [zonula adherens]
GO:0007018 [microtubule-based movement]
GO:0007601 [visual perception]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0045218 [zonula adherens maintenance]
GO:0070062 [extracellular exosome]
GO:0090136 [epithelial cell-cell adhesion]
Show all
 687 aa
77.1 kDa 		No 0
KIFC3-011
ENSP00000454632
ENST00000565351
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
 5 aa
0.6 kDa 		No 0
KIFC3-013
ENSP00000455276
ENST00000565684
H3BPE2 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 132 aa
14 kDa 		No 0
KIFC3-014
ENSP00000456354
ENST00000563028
H3BRQ1 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 155 aa
16.7 kDa 		No 0
KIFC3-017
ENSP00000457568
ENST00000565397
H3BUC0 [Direct mapping]
Kinesin-like protein
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 196 aa
20.2 kDa 		No 0
KIFC3-018
ENSP00000457232
ENST00000565270
H3BTL6 [Direct mapping]
Kinesin-like protein
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
Show all
 280 aa
30.7 kDa 		No 0
KIFC3-020
ENSP00000457948
ENST00000569222
H3BV47 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 104 aa
12.1 kDa 		No 0
KIFC3-021
ENSP00000457144
ENST00000567059
H3BTE9 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 166 aa
17.6 kDa 		No 0
KIFC3-023
ENSP00000456402
ENST00000569619
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
 5 aa
0.6 kDa 		No 0
KIFC3-025
ENSP00000457247
ENST00000569112
H3BTN1 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 60 aa
6.9 kDa 		No 0
KIFC3-026
ENSP00000454501
ENST00000562311
H3BMR0 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 70 aa
8.1 kDa 		No 0
KIFC3-027
ENSP00000457326
ENST00000565481
H3BTU1 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 147 aa
16.9 kDa 		No 0
KIFC3-028
ENSP00000454403
ENST00000562984
H3BMJ1 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 59 aa
6.8 kDa 		No 0
KIFC3-030
ENSP00000456780
ENST00000566648
H3BSN2 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 190 aa
21.1 kDa 		No 0
KIFC3-031
ENSP00000455067
ENST00000564891
H3BNZ0 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 105 aa
11 kDa 		No 0
KIFC3-033
ENSP00000454493
ENST00000562503
H3BMQ3 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 167 aa
19.3 kDa 		No 0
KIFC3-034
ENSP00000454615
ENST00000561524
H3BMZ5 [Direct mapping]
Kinesin-like protein KIFC3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
Show all
 88 aa
10.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.