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Weak to moderate cytoplasmic staining was observed in most malignant cells. A few cases of colorectal, prostate and gastric adenocarcinomas were strongly stained. Several lung and endometrial cancers were negative.
Most of the malignant cells showed weak to moderate nuclear positivity with additional cytoplasmic immunoreactivity in several cases. Most cases of liver cancers were negative.
GENE INFORMATION
Gene name
TIGD7 (HGNC Symbol)
Synonyms
Sancho
Description
Tigger transposable element derived 7 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
