Expression of SLC39A3 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 39 (zinc transporter), member 3

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042139	HPA058526

GENE INFORMATION
Gene name	SLC39A3 (HGNC Symbol)
Synonyms	ZIP3
Description	Solute carrier family 39 (zinc transporter), member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	2732204 - 2740152
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000141873 (version 83.38)
Entrez gene	29985
UniProt	Q9BRY0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRY0
Antibodypedia	SLC39A3 antibodies

PROTEIN BROWSER

SLC39A3-001	SLC39A3-002	SLC39A3-003	SLC39A3-004	SLC39A3-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC39A3-001 ENSP00000393715 ENST00000455372	Q9BRY0 [Direct mapping] Zinc transporter ZIP3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005385 [zinc ion transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0071577 [zinc II ion transmembrane transport] Show all	105 aa 11.5 kDa	No	1
SLC39A3-002 ENSP00000269740 ENST00000269740	Q9BRY0 [Direct mapping] Zinc transporter ZIP3 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000902 [cell morphogenesis] GO:0001701 [in utero embryonic development] GO:0005385 [zinc ion transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0006829 [zinc II ion transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0043029 [T cell homeostasis] GO:0046873 [metal ion transmembrane transporter activity] GO:0048701 [embryonic cranial skeleton morphogenesis] GO:0055085 [transmembrane transport] GO:0060173 [limb development] GO:0071577 [zinc II ion transmembrane transport] Show all	314 aa 33.6 kDa	No	8
SLC39A3-003 ENSP00000445345 ENST00000545664	F5H385 [Direct mapping] Zinc transporter ZIP3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	323 aa 34.6 kDa	No	8
SLC39A3-004 ENSP00000465383 ENST00000589363	K7EJZ1 [Direct mapping] Zinc transporter ZIP3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	136 aa 15.1 kDa	No	2
SLC39A3-006 ENSP00000466969 ENST00000589166	K7ENJ1 [Direct mapping] Zinc transporter ZIP3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] Show all	107 aa 11.9 kDa	No	2