Expression of DMRTC2 in cancer - Summary

CANCER ATLAS

Gene description

DMRT-like family C2

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045016

GENE INFORMATION
Gene name	DMRTC2
Synonyms
Description	DMRT-like family C2 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.2
Chromosome location (bp)	41844743 - 41852333
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000142025 (version 83.38)
Entrez gene	63946
UniProt	Q8IXT2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IXT2
Antibodypedia	DMRTC2 antibodies

PROTEIN BROWSER

DMRTC2-001	DMRTC2-003	DMRTC2-004	DMRTC2-006	DMRTC2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DMRTC2-001 ENSP00000269945 ENST00000269945	Q8IXT2 [Direct mapping] Doublesex- and mab-3-related transcription factor C2 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0000987 [core promoter proximal region sequence-specific DNA binding] GO:0001741 [XY body] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007141 [male meiosis I] GO:0007290 [spermatid nucleus elongation] GO:0007548 [sex differentiation] GO:0030154 [cell differentiation] GO:0042803 [protein homodimerization activity] GO:0043565 [sequence-specific DNA binding] GO:0046872 [metal ion binding] GO:1900111 [positive regulation of histone H3-K9 dimethylation] GO:1900114 [positive regulation of histone H3-K9 trimethylation] Show all	367 aa 39.1 kDa	No	0
DMRTC2-003 ENSP00000469525 ENST00000596827	B4DX56 [Direct mapping] Doublesex- and mab-3-related transcription factor C2; cDNA FLJ61444, highly similar to Doublesex- and mab-3-related transcription factor C2 Show all	Predicted intracellular proteins Show all	GO:0000987 [core promoter proximal region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007548 [sex differentiation] GO:0042803 [protein homodimerization activity] GO:0043565 [sequence-specific DNA binding] Show all	418 aa 44.8 kDa	No	0
DMRTC2-004 ENSP00000472488 ENST00000600017	M0R2D7 [Direct mapping] Doublesex- and mab-3-related transcription factor C2 Show all	Predicted intracellular proteins Show all	GO:0000987 [core promoter proximal region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007548 [sex differentiation] GO:0042803 [protein homodimerization activity] GO:0043565 [sequence-specific DNA binding] Show all	165 aa 18.2 kDa	No	0
DMRTC2-006 ENSP00000472215 ENST00000596258	M0R1Z9 [Direct mapping] Doublesex- and mab-3-related transcription factor C2 Show all	Predicted intracellular proteins Show all	GO:0000987 [core promoter proximal region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007548 [sex differentiation] GO:0042803 [protein homodimerization activity] GO:0043565 [sequence-specific DNA binding] Show all	135 aa 15.3 kDa	No	0
DMRTC2-007 ENSP00000470553 ENST00000596660	M0QZH7 [Direct mapping] Doublesex- and mab-3-related transcription factor C2 Show all	Predicted intracellular proteins Show all	GO:0000987 [core promoter proximal region sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0007548 [sex differentiation] GO:0042803 [protein homodimerization activity] GO:0043565 [sequence-specific DNA binding] Show all	161 aa 17.8 kDa	No	0