Expression of RPS11 in cancer - Summary

CANCER ATLAS

Gene description

Ribosomal protein S11

Protein class

Plasma proteins, Predicted intracellular proteins, Ribosomal proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049719

GENE INFORMATION
Gene name	RPS11 (HGNC Symbol)
Synonyms	S11
Description	Ribosomal protein S11 (HGNC Symbol)
Entrez gene summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012]
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	49496365 - 49499689
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000142534 (version 83.38)
Entrez gene	6205
UniProt	P62280 (UniProt - Evidence at protein level)
neXtProt	NX_P62280
Antibodypedia	RPS11 antibodies

PROTEIN BROWSER

RPS11-001	RPS11-003	RPS11-006	RPS11-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPS11-001 ENSP00000270625 ENST00000270625	P62280 [Direct mapping] 40S ribosomal protein S11 Show all	Ribosomal proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0001649 [osteoblast differentiation] GO:0003735 [structural constituent of ribosome] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005840 [ribosome] GO:0005925 [focal adhesion] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006414 [translational elongation] GO:0006415 [translational termination] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0019058 [viral life cycle] GO:0019083 [viral transcription] GO:0019843 [rRNA binding] GO:0022627 [cytosolic small ribosomal subunit] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] Show all	158 aa 18.4 kDa	No	0
RPS11-003 ENSP00000471873 ENST00000594493	M0R1H5 [Direct mapping] 40S ribosomal protein S11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] Show all	79 aa 9.5 kDa	No	0
RPS11-006 ENSP00000470447 ENST00000596873	M0QZC5 [Direct mapping] 40S ribosomal protein S11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] Show all	118 aa 14 kDa	No	0
RPS11-008 ENSP00000471874 ENST00000599561	M0R1H6 [Direct mapping] 40S ribosomal protein S11 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005840 [ribosome] GO:0006412 [translation] Show all	88 aa 10.1 kDa	No	0