Expression of NOSIP in cancer - Summary

CANCER ATLAS

Gene description

Nitric oxide synthase interacting protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Pancreatic cancer

STAINING SUMMARY

HPA043464

GENE INFORMATION
Gene name	NOSIP (HGNC Symbol)
Synonyms	CGI-25
Description	Nitric oxide synthase interacting protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	49555711 - 49590262
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000142546 (version 83.38)
Entrez gene	51070
UniProt	Q9Y314 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y314
Antibodypedia	NOSIP antibodies

PROTEIN BROWSER

NOSIP-001	NOSIP-004	NOSIP-005	NOSIP-008	NOSIP-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NOSIP-001 ENSP00000470034 ENST00000596358	Q9Y314 [Direct mapping] Nitric oxide synthase-interacting protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0043086 [negative regulation of catalytic activity] GO:0044281 [small molecule metabolic process] GO:0044822 [poly(A) RNA binding] GO:0046209 [nitric oxide metabolic process] GO:0050999 [regulation of nitric-oxide synthase activity] GO:0051001 [negative regulation of nitric-oxide synthase activity] Show all	301 aa 33.2 kDa	No	0
NOSIP-004 ENSP00000473109 ENST00000599537	M0R3B2 [Direct mapping] Nitric oxide synthase-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0050999 [regulation of nitric-oxide synthase activity] Show all	242 aa 26.9 kDa	No	0
NOSIP-005 ENSP00000468974 ENST00000598544	M0QX85 [Direct mapping] Nitric oxide synthase-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0016567 [protein ubiquitination] GO:0050999 [regulation of nitric-oxide synthase activity] Show all	96 aa 11.1 kDa	No	0
NOSIP-008 ENSP00000343497 ENST00000339093	A0A075B6F9 [Direct mapping] Nitric oxide synthase-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0050999 [regulation of nitric-oxide synthase activity] Show all	304 aa 33.4 kDa	No	0
NOSIP-010 ENSP00000471929 ENST00000598296	M0R1K2 [Direct mapping] Nitric oxide synthase-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0050999 [regulation of nitric-oxide synthase activity] Show all	176 aa 19.7 kDa	No	0