Tissue expression of ARHGEF19 - Summary

GENERAL INFORMATION
Gene name	ARHGEF19
Gene description	Rho guanine nucleotide exchange factor (GEF) 19
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (skin)
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	ARHGEF19 (HGNC Symbol)
Synonyms	FLJ33962, WGEF
Description	Rho guanine nucleotide exchange factor (GEF) 19 (HGNC Symbol)
Entrez gene summary	Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]
Chromosome	1
Cytoband	p36.13
Chromosome location (bp)	16197854 - 16212609
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000142632 (version 83.38)
Entrez gene	128272
UniProt	Q8IW93 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IW93
Antibodypedia	ARHGEF19 antibodies

PROTEIN BROWSER

ARHGEF19-001	ARHGEF19-004	ARHGEF19-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGEF19-001 ENSP00000270747 ENST00000270747	Q8IW93 [Direct mapping] Rho guanine nucleotide exchange factor 19 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0032956 [regulation of actin cytoskeleton organization] GO:0035023 [regulation of Rho protein signal transduction] GO:0042060 [wound healing] GO:0043547 [positive regulation of GTPase activity] Show all	802 aa 89.2 kDa	No	0
ARHGEF19-004 ENSP00000391145 ENST00000449495	H0Y4D8 [Direct mapping] Rho guanine nucleotide exchange factor 19 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	307 aa 34.5 kDa	No	0
ARHGEF19-007 ENSP00000414370 ENST00000441785	Q5TEV0 [Direct mapping] Rho guanine nucleotide exchange factor 19 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	167 aa 18.7 kDa	No	0