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RPL11

CANCER ATLAS

Gene description

 Ribosomal protein L11

Protein class

 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA002734

GENE INFORMATION

Gene name

 RPL11 (HGNC Symbol)

Synonyms

 L11

Description

 Ribosomal protein L11 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2010]

Chromosome

 1

Cytoband

 p36.11

Chromosome location (bp)

 23691779 - 23696425

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000142676 (version 83.38)

Entrez gene

 6135

UniProt

 P62913 (UniProt - Evidence at protein level)

neXtProt

 NX_P62913

Antibodypedia

 RPL11 antibodies

PROTEIN BROWSER
RPL11-001
RPL11-004
RPL11-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL11-001
ENSP00000363676
ENST00000374550
P62913 [Direct mapping]
60S ribosomal protein L11
Q5VVD0 [Target identity:100%; Query identity:100%]
Ribosomal protein L11, isoform CRA_b; cDNA, FLJ92077, Homo sapiens ribosomal protein L11 (RPL11), mRNA
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Ribosomal proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000027 [ribosomal large subunit assembly]
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006364 [rRNA processing]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006605 [protein targeting]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019843 [rRNA binding]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0034504 [protein localization to nucleus]
GO:0042273 [ribosomal large subunit biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0070062 [extracellular exosome]
Show all
 178 aa
20.3 kDa 		No 0
RPL11-004
ENSP00000390839
ENST00000443624
Q5VVC9 [Direct mapping]
60S ribosomal protein L11
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 131 aa
14.9 kDa 		No 0
RPL11-005
ENSP00000398888
ENST00000458455
Q5VVC8 [Direct mapping]
60S ribosomal protein L11
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 174 aa
20 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.