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UFC1

GENERAL INFORMATION

Gene name

 UFC1

Gene description

 Ubiquitin-fold modifier conjugating enzyme 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression at variable levels in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA027481 , HPA028722
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Nasopharynx

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 UFC1 (HGNC Symbol)

Synonyms

 HSPC155

Description

 Ubiquitin-fold modifier conjugating enzyme 1 (HGNC Symbol)

Entrez gene summary

 UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Mar 2008]

Chromosome

 1

Cytoband

 q23.3

Chromosome location (bp)

 161152776 - 161158856

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000143222 (version 83.38)

Entrez gene

 51506

UniProt

 Q9Y3C8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y3C8

Antibodypedia

 UFC1 antibodies

PROTEIN BROWSER
UFC1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UFC1-001
ENSP00000356982
ENST00000368003
Q9Y3C8 [Direct mapping]
Ubiquitin-fold modifier-conjugating enzyme 1
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0034976 [response to endoplasmic reticulum stress]
GO:0070062 [extracellular exosome]
GO:0071568 [UFM1 transferase activity]
GO:0071569 [protein ufmylation]
GO:1990592 [protein K69-linked ufmylation]
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 167 aa
19.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.