We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
This gene encodes the skeletal muscle specific member of the calsequestrin protein family. Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells. This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle. This protein is absent in patients with Duchenne and Becker types of muscular dystrophy. [provided by RefSeq, Jun 2013]
MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0005783 [endoplasmic reticulum] GO:0005790 [smooth endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0007029 [endoplasmic reticulum organization] GO:0007519 [skeletal muscle tissue development] GO:0009408 [response to heat] GO:0010033 [response to organic substance] GO:0010880 [regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum] GO:0014802 [terminal cisterna] GO:0014804 [terminal cisterna lumen] GO:0014809 [regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion] GO:0014870 [response to muscle inactivity] GO:0014894 [response to denervation involved in regulation of muscle adaptation] GO:0016529 [sarcoplasmic reticulum] GO:0030016 [myofibril] GO:0030315 [T-tubule] GO:0031674 [I band] GO:0033017 [sarcoplasmic reticulum membrane] GO:0033018 [sarcoplasmic reticulum lumen] GO:0034220 [ion transmembrane transport] GO:0042383 [sarcolemma] GO:0043231 [intracellular membrane-bounded organelle] GO:0045214 [sarcomere organization] GO:0051258 [protein polymerization] GO:0051282 [regulation of sequestering of calcium ion] GO:0055085 [transmembrane transport]
