Cell atlas - RGS16 - The Human Protein Atlas

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RGS16

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	RGS16
Gene description	Regulator of G-protein signaling 16
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Cell line enhanced (SCLC-21H, U-698, U-266/70, Daudi)
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA053250
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, U-698, U-266/70, Daudi) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA053250	MCF7	No staining
	HPA053250	U-2 OS	Cytosol

GENE INFORMATION
Gene name	RGS16 (HGNC Symbol)
Synonyms	A28-RGS14, RGS-r
Description	Regulator of G-protein signaling 16 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q25.3
Chromosome location (bp)	182598623 - 182604408
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143333 (version 83.38)
Entrez gene	6004
UniProt	O15492 (UniProt - Evidence at protein level)
neXtProt	NX_O15492
Antibodypedia	RGS16 antibodies

PROTEIN BROWSER

RGS16-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RGS16-001 ENSP00000356529 ENST00000367558	O15492 [Direct mapping] Regulator of G-protein signaling 16 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0007601 [visual perception] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0009968 [negative regulation of signal transduction] GO:0043547 [positive regulation of GTPase activity] GO:0045121 [membrane raft] Show all	202 aa 22.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.