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A majority of renal and endometrial cancers showed moderate to strong cytoplasmic immunoreactivity while cases of lymphomas, melanomas, breast, pancreatic, ovarian and hepatocellular carcinomas showed moderate positivity. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
SMYD2 (HGNC Symbol)
Synonyms
HSKM-B, KMT3C, ZMYND14
Description
SET and MYND domain containing 2 (HGNC Symbol)
Entrez gene summary
SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]