Expression of JTB in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Jumping translocation breakpoint

Protein class

Cancer-related genes, Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA006514

GENE INFORMATION
Gene name	JTB (HGNC Symbol)
Synonyms	hJT
Description	Jumping translocation breakpoint (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	153974269 - 153977688
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143543 (version 83.38)
Entrez gene	10899
UniProt	O76095 (UniProt - Evidence at protein level)
neXtProt	NX_O76095
Antibodypedia	JTB antibodies

PROTEIN BROWSER

JTB-001	JTB-002	JTB-003	JTB-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
JTB-001 ENSP00000271843 ENST00000271843	O76095 [Direct mapping] Protein JTB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005887 [integral component of plasma membrane] GO:0007067 [mitotic nuclear division] GO:0008637 [apoptotic mitochondrial changes] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0042127 [regulation of cell proliferation] GO:0045860 [positive regulation of protein kinase activity] Show all	146 aa 16.4 kDa	Yes	1
JTB-002 ENSP00000349069 ENST00000356648	O76095 [Direct mapping] Protein JTB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005887 [integral component of plasma membrane] GO:0007067 [mitotic nuclear division] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0045860 [positive regulation of protein kinase activity] Show all	117 aa 13.4 kDa	Yes	1
JTB-003 ENSP00000357578 ENST00000368589	O76095 [Direct mapping] Protein JTB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005887 [integral component of plasma membrane] GO:0007067 [mitotic nuclear division] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0045860 [positive regulation of protein kinase activity] Show all	117 aa 13.4 kDa	Yes	1
JTB-006 ENSP00000395250 ENST00000428469	O76095 [Direct mapping] Protein JTB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Ezkurdia et al 2014) Show all	GO:0000910 [cytokinesis] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005819 [spindle] GO:0005887 [integral component of plasma membrane] GO:0007067 [mitotic nuclear division] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019901 [protein kinase binding] GO:0030496 [midbody] GO:0045860 [positive regulation of protein kinase activity] Show all	117 aa 13.4 kDa	Yes	1