P49810 [Direct mapping]
Presenilin-2 Presenilin-2 NTF subunit Presenilin-2 CTF subunit

GO:0000139 [Golgi membrane]
GO:0000776 [kinetochore]
GO:0001666 [response to hypoxia]
GO:0001708 [cell fate specification]
GO:0001756 [somitogenesis]
GO:0001933 [negative regulation of protein phosphorylation]
GO:0001942 [hair follicle development]
GO:0002244 [hematopoietic progenitor cell differentiation]
GO:0002286 [T cell activation involved in immune response]
GO:0002573 [myeloid leukocyte differentiation]
GO:0004175 [endopeptidase activity]
GO:0004190 [aspartic-type endopeptidase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005637 [nuclear inner membrane]
GO:0005743 [mitochondrial inner membrane]
GO:0005765 [lysosomal membrane]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005794 [Golgi apparatus]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0005938 [cell cortex]
GO:0006509 [membrane protein ectodomain proteolysis]
GO:0006816 [calcium ion transport]
GO:0007176 [regulation of epidermal growth factor-activated receptor activity]
GO:0007219 [Notch signaling pathway]
GO:0007220 [Notch receptor processing]
GO:0007411 [axon guidance]
GO:0007611 [learning or memory]
GO:0007613 [memory]
GO:0009986 [cell surface]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0016485 [protein processing]
GO:0021904 [dorsal/ventral neural tube patterning]
GO:0030018 [Z disc]
GO:0030326 [embryonic limb morphogenesis]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030900 [forebrain development]
GO:0031293 [membrane protein intracellular domain proteolysis]
GO:0031333 [negative regulation of protein complex assembly]
GO:0031594 [neuromuscular junction]
GO:0032091 [negative regulation of protein binding]
GO:0032469 [endoplasmic reticulum calcium ion homeostasis]
GO:0035253 [ciliary rootlet]
GO:0035556 [intracellular signal transduction]
GO:0036064 [ciliary basal body]
GO:0040011 [locomotion]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043025 [neuronal cell body]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043085 [positive regulation of catalytic activity]
GO:0043198 [dendritic shaft]
GO:0043234 [protein complex]
GO:0043393 [regulation of protein binding]
GO:0044267 [cellular protein metabolic process]
GO:0045121 [membrane raft]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048013 [ephrin receptor signaling pathway]
GO:0048167 [regulation of synaptic plasticity]
GO:0048286 [lung alveolus development]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048538 [thymus development]
GO:0048854 [brain morphogenesis]
GO:0050435 [beta-amyloid metabolic process]
GO:0050820 [positive regulation of coagulation]
GO:0050852 [T cell receptor signaling pathway]
GO:0051604 [protein maturation]
GO:0060048 [cardiac muscle contraction]
GO:0097190 [apoptotic signaling pathway]
GO:1902042 [negative regulation of extrinsic apoptotic signaling pathway via death domain receptors]
GO:2001234 [negative regulation of apoptotic signaling pathway]

E5RHT1 [Direct mapping]
Presenilin-2

GO:0004175 [endopeptidase activity]
GO:0004190 [aspartic-type endopeptidase activity]
GO:0005634 [nucleus]
GO:0005743 [mitochondrial inner membrane]
GO:0005765 [lysosomal membrane]
GO:0005938 [cell cortex]
GO:0006508 [proteolysis]
GO:0006816 [calcium ion transport]
GO:0009986 [cell surface]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0030018 [Z disc]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0031594 [neuromuscular junction]
GO:0035253 [ciliary rootlet]
GO:0035556 [intracellular signal transduction]
GO:0043025 [neuronal cell body]
GO:0043066 [negative regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0045121 [membrane raft]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050435 [beta-amyloid metabolic process]

E5RG63 [Direct mapping]
Presenilin

GO:0000139 [Golgi membrane]
GO:0004175 [endopeptidase activity]
GO:0004190 [aspartic-type endopeptidase activity]
GO:0005634 [nucleus]
GO:0005743 [mitochondrial inner membrane]
GO:0005765 [lysosomal membrane]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005938 [cell cortex]
GO:0006508 [proteolysis]
GO:0006816 [calcium ion transport]
GO:0007219 [Notch signaling pathway]
GO:0009986 [cell surface]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0030018 [Z disc]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0031594 [neuromuscular junction]
GO:0035253 [ciliary rootlet]
GO:0035556 [intracellular signal transduction]
GO:0043025 [neuronal cell body]
GO:0043066 [negative regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0045121 [membrane raft]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050435 [beta-amyloid metabolic process]

E5RJM5 [Direct mapping]
Presenilin-2

GO:0004175 [endopeptidase activity]
GO:0005634 [nucleus]
GO:0005743 [mitochondrial inner membrane]
GO:0005765 [lysosomal membrane]
GO:0005938 [cell cortex]
GO:0006508 [proteolysis]
GO:0006816 [calcium ion transport]
GO:0009986 [cell surface]
GO:0016324 [apical plasma membrane]
GO:0030018 [Z disc]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0031594 [neuromuscular junction]
GO:0035253 [ciliary rootlet]
GO:0043025 [neuronal cell body]
GO:0043066 [negative regulation of apoptotic process]
GO:0043198 [dendritic shaft]
GO:0045121 [membrane raft]
GO:0048471 [perinuclear region of cytoplasm]
GO:0050435 [beta-amyloid metabolic process]