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HNRNPLL

CANCER ATLAS

Gene description

 Heterogeneous nuclear ribonucleoprotein L-like

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA046084

GENE INFORMATION

Gene name

 HNRNPLL (HGNC Symbol)

Synonyms

 HNRPLL

Description

 Heterogeneous nuclear ribonucleoprotein L-like (HGNC Symbol)

Entrez gene summary

 HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]

Chromosome

 2

Cytoband

 p22.1

Chromosome location (bp)

 38561978 - 38603586

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000143889 (version 83.38)

Entrez gene

 92906

UniProt

 Q8WVV9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WVV9

Antibodypedia

 HNRNPLL antibodies

PROTEIN BROWSER
HNRNPLL-001
HNRNPLL-002
HNRNPLL-004
HNRNPLL-007
HNRNPLL-008
HNRNPLL-010
HNRNPLL-201
HNRNPLL-202
HNRNPLL-203

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HNRNPLL-001
ENSP00000390625
ENST00000449105
Q8WVV9 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0016020 [membrane]
GO:0030529 [ribonucleoprotein complex]
GO:0033120 [positive regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
Show all
 542 aa
60.1 kDa 		No 0
HNRNPLL-002
ENSP00000387088
ENST00000409636
Q8WVV9 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0016020 [membrane]
GO:0030529 [ribonucleoprotein complex]
GO:0033120 [positive regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
Show all
 537 aa
59.6 kDa 		No 0
HNRNPLL-004
ENSP00000386695
ENST00000410076
Q8WVV9 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0016020 [membrane]
GO:0030529 [ribonucleoprotein complex]
GO:0033120 [positive regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
Show all
 275 aa
30.8 kDa 		No 0
HNRNPLL-007
ENSP00000396669
ENST00000425682
C9JJZ7 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
Show all
 149 aa
16.4 kDa 		No 0
HNRNPLL-008
ENSP00000415766
ENST00000441689
H7C464 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
Show all
 133 aa
14.9 kDa 		No 0
HNRNPLL-010
ENSP00000386575
ENST00000409328
Q8WVV9 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0003729 [mRNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0016020 [membrane]
GO:0030529 [ribonucleoprotein complex]
GO:0033120 [positive regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
Show all
 508 aa
56.5 kDa 		No 0
HNRNPLL-201
ENSP00000351136
ENST00000358367
C9IYN3 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like; Heterogeneous nuclear ribonucleoprotein L-like, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0019013 [viral nucleocapsid]
GO:0030529 [ribonucleoprotein complex]
Show all
 537 aa
59.7 kDa 		No 0
HNRNPLL-202
ENSP00000368195
ENST00000378915
B7WPG3 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
Show all
 508 aa
56.5 kDa 		No 0
HNRNPLL-203
ENSP00000476852
ENST00000608859
D6W592 [Direct mapping]
Heterogeneous nuclear ribonucleoprotein L-like; Heterogeneous nuclear ribonucleoprotein L-like, isoform CRA_d
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0006397 [mRNA processing]
GO:0019013 [viral nucleocapsid]
GO:0030529 [ribonucleoprotein complex]
Show all
 542 aa
60.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.