Cell atlas - GALM - The Human Protein Atlas

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GALM

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	GALM
Gene description	Galactose mutarotase (aldose 1-epimerase)
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035473
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035473	A-431	Nucleoplasm
	HPA035473	Hep G2	Nucleoplasm
	HPA035473	U-2 OS	No staining

GENE INFORMATION
Gene name	GALM
Synonyms
Description	Galactose mutarotase (aldose 1-epimerase) (HGNC Symbol)
Entrez gene summary	This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose.[provided by RefSeq, Mar 2009]
Chromosome	2
Cytoband	p22.1
Chromosome location (bp)	38665910 - 38741237
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143891 (version 83.38)
Entrez gene	130589
UniProt	Q96C23 (UniProt - Evidence at protein level)
neXtProt	NX_Q96C23
Antibodypedia	GALM antibodies

PROTEIN BROWSER

GALM-001	GALM-003	GALM-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GALM-001 ENSP00000272252 ENST00000272252	Q96C23 [Direct mapping] Aldose 1-epimerase Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004034 [aldose 1-epimerase activity] GO:0005737 [cytoplasm] GO:0005975 [carbohydrate metabolic process] GO:0006006 [glucose metabolic process] GO:0006012 [galactose metabolic process] GO:0016853 [isomerase activity] GO:0019318 [hexose metabolic process] GO:0030246 [carbohydrate binding] GO:0070062 [extracellular exosome] Show all	342 aa 37.8 kDa	No	0
GALM-003 ENSP00000386233 ENST00000410063	B8ZZ75 [Direct mapping] Aldose 1-epimerase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005975 [carbohydrate metabolic process] GO:0016853 [isomerase activity] GO:0030246 [carbohydrate binding] Show all	194 aa 21.5 kDa	No	0
GALM-005 ENSP00000399473 ENST00000434934	H7C1B5 [Direct mapping] Aldose 1-epimerase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005975 [carbohydrate metabolic process] GO:0016853 [isomerase activity] GO:0030246 [carbohydrate binding] Show all	218 aa 24.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.