Tissue expression of VPS54 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	VPS54
Gene description	Vacuolar protein sorting 54 homolog (S. cerevisiae)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	VPS54 (HGNC Symbol)
Synonyms	HCC8, PPP1R164
Description	Vacuolar protein sorting 54 homolog (S. cerevisiae) (HGNC Symbol)
Entrez gene summary	This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband
Chromosome location (bp)	63892146 - 64019072
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000143952 (version 83.38)
Entrez gene	51542
UniProt	Q9P1Q0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P1Q0
Antibodypedia	VPS54 antibodies

PROTEIN BROWSER

VPS54-001	VPS54-002	VPS54-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VPS54-001 ENSP00000272322 ENST00000272322	Q9P1Q0 [Direct mapping] Vacuolar protein sorting-associated protein 54 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000938 [GARP complex] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005802 [trans-Golgi network] GO:0006896 [Golgi to vacuole transport] GO:0015031 [protein transport] GO:0019905 [syntaxin binding] GO:0040007 [growth] GO:0042147 [retrograde transport, endosome to Golgi] GO:0048471 [perinuclear region of cytoplasm] GO:0048873 [homeostasis of number of cells within a tissue] GO:0050881 [musculoskeletal movement] GO:0060052 [neurofilament cytoskeleton organization] Show all	977 aa 110.6 kDa	No	0
VPS54-002 ENSP00000386980 ENST00000409558	Q9P1Q0 [Direct mapping] Vacuolar protein sorting-associated protein 54 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000938 [GARP complex] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005802 [trans-Golgi network] GO:0006896 [Golgi to vacuole transport] GO:0015031 [protein transport] GO:0019905 [syntaxin binding] GO:0042147 [retrograde transport, endosome to Golgi] GO:0048471 [perinuclear region of cytoplasm] Show all	965 aa 109.4 kDa	No	0
VPS54-003 ENSP00000346499 ENST00000354504	Q9P1Q0 [Direct mapping] Vacuolar protein sorting-associated protein 54 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000938 [GARP complex] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005794 [Golgi apparatus] GO:0005802 [trans-Golgi network] GO:0006896 [Golgi to vacuole transport] GO:0015031 [protein transport] GO:0019905 [syntaxin binding] GO:0042147 [retrograde transport, endosome to Golgi] GO:0048471 [perinuclear region of cytoplasm] Show all	824 aa 93.3 kDa	No	0