Expression of NAT8 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

N-acetyltransferase 8 (GCN5-related, putative)

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

CAB045990

GENE INFORMATION
Gene name	NAT8 (HGNC Symbol)
Synonyms	ATase2, GLA, Hcml1, TSC501
Description	N-acetyltransferase 8 (GCN5-related, putative) (HGNC Symbol)
Entrez gene summary	This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008]
Chromosome	2
Cytoband	p13.1
Chromosome location (bp)	73640832 - 73642393
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144035 (version 83.38)
Entrez gene	9027
UniProt	Q9UHE5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UHE5
Antibodypedia	NAT8 antibodies

PROTEIN BROWSER

NAT8-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAT8-001 ENSP00000272425 ENST00000272425	Q9UHE5 [Direct mapping] N-acetyltransferase 8 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004468 [lysine N-acetyltransferase activity, acting on acetyl phosphate as donor] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006749 [glutathione metabolic process] GO:0008080 [N-acetyltransferase activity] GO:0010628 [positive regulation of gene expression] GO:0016021 [integral component of membrane] GO:0018003 [peptidyl-lysine N6-acetylation] GO:0033116 [endoplasmic reticulum-Golgi intermediate compartment membrane] GO:0042493 [response to drug] GO:0043066 [negative regulation of apoptotic process] GO:0044267 [cellular protein metabolic process] GO:0047198 [cysteine-S-conjugate N-acetyltransferase activity] GO:0050435 [beta-amyloid metabolic process] GO:0070062 [extracellular exosome] Show all	227 aa 25.6 kDa	No	2