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RABL2A

GENERAL INFORMATION

Gene name

 RABL2A

Gene description

 RAB, member of RAS oncogene family-like 2A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (fallopian tube)
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression mainly in fallopian tube and respiratory epithelia.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 2 antibodies.
HPA042700 , HPA044007
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Fallopian tube

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 RABL2A

Synonyms

Description

 RAB, member of RAS oncogene family-like 2A (HGNC Symbol)

Entrez gene summary

 This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Chromosome

 2

Cytoband

 q14.1

Chromosome location (bp)

 113627229 - 113643396

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000144134 (version 83.38)

Entrez gene

 11159

UniProt

 Q9UBK7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UBK7

Antibodypedia

 RABL2A antibodies

PROTEIN BROWSER
RABL2A-001
RABL2A-002
RABL2A-003
RABL2A-004
RABL2A-008
RABL2A-013
RABL2A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RABL2A-001
ENSP00000376871
ENST00000393166
Q9UBK7 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 228 aa
26.1 kDa 		No 0
RABL2A-002
ENSP00000376872
ENST00000393167
Q9UBK7 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 228 aa
26.1 kDa 		No 0
RABL2A-003
ENSP00000376870
ENST00000393165
Q9UBK7 [Direct mapping]
Rab-like protein 2A
Q6IC14 [Target identity:100%; Query identity:100%]
RABL2A protein; RABL2B protein; cDNA FLJ78724, highly similar to Homo sapiens RAB, member of RAS oncogene family-like 2B (RABL2B), transcript variant 1, mRNA
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Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 229 aa
26.2 kDa 		No 0
RABL2A-004
ENSP00000388944
ENST00000413545
B7ZBD4 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0032482 [Rab protein signal transduction]
Show all
 114 aa
13 kDa 		No 0
RABL2A-008
ENSP00000386460
ENST00000409842
B7ZBD5 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0032482 [Rab protein signal transduction]
Show all
 165 aa
18.5 kDa 		No 0
RABL2A-013
ENSP00000387229
ENST00000409875
Q9UBK7 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 238 aa
27.2 kDa 		No 0
RABL2A-201
ENSP00000365622
ENST00000376439
B7ZBD5 [Direct mapping]
Rab-like protein 2A
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0032482 [Rab protein signal transduction]
Show all
 165 aa
18.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.