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SPAG16

CANCER ATLAS

Gene description

 Sperm associated antigen 16

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037542

GENE INFORMATION

Gene name

 SPAG16 (HGNC Symbol)

Synonyms

 DKFZp666P1710, FLJ22724, PF20, WDR29

Description

 Sperm associated antigen 16 (HGNC Symbol)

Entrez gene summary

 Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]

Chromosome

 2

Cytoband

 q34

Chromosome location (bp)

 213284379 - 214410501

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000144451 (version 83.38)

Entrez gene

 79582

UniProt

 Q8N0X2 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8N0X2

Antibodypedia

 SPAG16 antibodies

PROTEIN BROWSER
SPAG16-001
SPAG16-002
SPAG16-004
SPAG16-006
SPAG16-007
SPAG16-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SPAG16-001
ENSP00000332592
ENST00000331683
Q8N0X2 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005930 [axoneme]
GO:0007288 [sperm axoneme assembly]
GO:0019901 [protein kinase binding]
GO:0031514 [motile cilium]
GO:0035082 [axoneme assembly]
GO:0042384 [cilium assembly]
GO:0051012 [microtubule sliding]
GO:0060294 [cilium movement involved in cell motility]
GO:0097231 [cell motility in response to calcium ion]
GO:1990716 [axonemal central apparatus]
Show all
 631 aa
70.8 kDa 		No 0
SPAG16-002
ENSP00000415079
ENST00000432529
Q8N0X2 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
Show all
GO:0005856 [cytoskeleton]
GO:0005930 [axoneme]
GO:0031514 [motile cilium]
GO:0035082 [axoneme assembly]
GO:0042384 [cilium assembly]
Show all
 183 aa
20.6 kDa 		No 0
SPAG16-004
ENSP00000390494
ENST00000413312
A0A0C4DG20 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
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 251 aa
29.1 kDa 		No 0
SPAG16-006
ENSP00000400847
ENST00000447990
E7EWV3 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
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 374 aa
42.8 kDa 		No 0
SPAG16-007
ENSP00000416600
ENST00000451561
H0Y811 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
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GO:0005515 [protein binding]
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 255 aa
28.2 kDa 		No 0
SPAG16-201
ENSP00000272898
ENST00000272898
A0A0A0MQX0 [Direct mapping]
Sperm-associated antigen 16 protein
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Predicted intracellular proteins
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 318 aa
36.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.