Expression of POMGNT2 in cancer - Summary

CANCER ATLAS

Gene description

Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)

Protein class

Disease related genes, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA034870	HPA040989

GENE INFORMATION
Gene name	POMGNT2 (HGNC Symbol)
Synonyms	AGO61, C3orf39, FLJ14566, GTDC2
Description	Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) (HGNC Symbol)
Entrez gene summary	This gene encodes a protein with glycosyltransferase activity although its function is not currently known. [provided by RefSeq, Sep 2012]
Chromosome	3
Cytoband	p22.1
Chromosome location (bp)	43079232 - 43106076
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144647 (version 83.38)
Entrez gene	84892
UniProt	Q8NAT1 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NAT1
Antibodypedia	POMGNT2 antibodies

PROTEIN BROWSER

POMGNT2-001	POMGNT2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POMGNT2-001 ENSP00000344125 ENST00000344697	Q8NAT1 [Direct mapping] Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 A0A024R2P4 [Target identity:100%; Query identity:100%] Chromosome 3 open reading frame 39, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001764 [neuron migration] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006493 [protein O-linked glycosylation] GO:0008375 [acetylglucosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0035269 [protein O-linked mannosylation] GO:0097363 [protein O-GlcNAc transferase activity] Show all	580 aa 66.6 kDa	Yes	0
POMGNT2-002 ENSP00000408992 ENST00000441964	Q8NAT1 [Direct mapping] Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 A0A024R2P4 [Target identity:100%; Query identity:100%] Chromosome 3 open reading frame 39, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0001764 [neuron migration] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006493 [protein O-linked glycosylation] GO:0008375 [acetylglucosaminyltransferase activity] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0035269 [protein O-linked mannosylation] GO:0097363 [protein O-GlcNAc transferase activity] Show all	580 aa 66.6 kDa	Yes	0