Expression of SLC25A38 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25, member 38

Protein class

Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041027

GENE INFORMATION
Gene name	SLC25A38 (HGNC Symbol)
Synonyms	FLJ20551
Description	Solute carrier family 25, member 38 (HGNC Symbol)
Entrez gene summary	This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia.[provided by RefSeq, Mar 2010]
Chromosome	3
Cytoband	p22.1
Chromosome location (bp)	39383348 - 39397351
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144659 (version 83.38)
Entrez gene	54977
UniProt	Q96DW6 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DW6
Antibodypedia	SLC25A38 antibodies

PROTEIN BROWSER

SLC25A38-001	SLC25A38-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A38-001 ENSP00000273158 ENST00000273158	Q96DW6 [Direct mapping] Solute carrier family 25 member 38 A0A024R2L5 [Target identity:100%; Query identity:100%] Solute carrier family 25 member 38 Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005743 [mitochondrial inner membrane] GO:0006783 [heme biosynthetic process] GO:0006810 [transport] GO:0016021 [integral component of membrane] GO:0030218 [erythrocyte differentiation] Show all	304 aa 33.6 kDa	No	0
SLC25A38-002 ENSP00000394244 ENST00000431510	C9JT44 [Direct mapping] Solute carrier family 25 member 38 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	148 aa 16.6 kDa	No	2