Expression of SLC25A26 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25 (S-adenosylmethionine carrier), member 26

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA026887

GENE INFORMATION
Gene name	SLC25A26
Synonyms
Description	Solute carrier family 25 (S-adenosylmethionine carrier), member 26 (HGNC Symbol)
Entrez gene summary	Mitochondrial carriers, including SLC25A26, are a family of transport proteins found mostly in the inner membranes of mitochondria. They shuttle metabolites and cofactors through the mitochondrial membrane (Agrimi et al., 2004 [PubMed 14674884]).[supplied by OMIM, Mar 2008]
Chromosome	3
Cytoband	p14.1
Chromosome location (bp)	66133610 - 66388116
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144741 (version 83.38)
Entrez gene	115286
UniProt	Q70HW3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q70HW3
Antibodypedia	SLC25A26 antibodies

PROTEIN BROWSER

SLC25A26-001	SLC25A26-002	SLC25A26-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A26-001 ENSP00000346955 ENST00000354883	F8WAB8 [Direct mapping] S-adenosylmethionine mitochondrial carrier protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	274 aa 29.4 kDa	No	4
SLC25A26-002 ENSP00000415304 ENST00000413054	H7C430 [Direct mapping] S-adenosylmethionine mitochondrial carrier protein Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0016021 [integral component of membrane] Show all	210 aa 22.6 kDa	No	0
SLC25A26-006 ENSP00000336801 ENST00000336733	Q70HW3 [Direct mapping] S-adenosylmethionine mitochondrial carrier protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000095 [S-adenosyl-L-methionine transmembrane transporter activity] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0015805 [S-adenosyl-L-methionine transport] GO:0016021 [integral component of membrane] GO:1901962 [S-adenosyl-L-methionine transmembrane transport] Show all	186 aa 20.1 kDa	No	1