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ABHD10

CANCER ATLAS

Gene description

 Abhydrolase domain containing 10

Protein class

 Enzymes, Predicted secreted proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036991
HPA036992

GENE INFORMATION

Gene name

 ABHD10 (HGNC Symbol)

Synonyms

 FLJ11342

Description

 Abhydrolase domain containing 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

 3

Cytoband

 q13.2

Chromosome location (bp)

 111979010 - 111993363

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000144827 (version 83.38)

Entrez gene

 55347

UniProt

 Q9NUJ1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NUJ1

Antibodypedia

 ABHD10 antibodies

PROTEIN BROWSER
ABHD10-001
ABHD10-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABHD10-001
ENSP00000273359
ENST00000273359
Q9NUJ1 [Direct mapping]
Mycophenolic acid acyl-glucuronide esterase, mitochondrial
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0005829 [cytosol]
GO:0006805 [xenobiotic metabolic process]
GO:0019391 [glucuronoside catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0052695 [cellular glucuronidation]
Show all
 306 aa
33.9 kDa 		Yes 0
ABHD10-005
ENSP00000418973
ENST00000494817
Q9NUJ1 [Direct mapping]
Mycophenolic acid acyl-glucuronide esterase, mitochondrial
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004553 [hydrolase activity, hydrolyzing O-glycosyl compounds]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0005829 [cytosol]
GO:0006805 [xenobiotic metabolic process]
GO:0019391 [glucuronoside catabolic process]
GO:0044281 [small molecule metabolic process]
GO:0052695 [cellular glucuronidation]
Show all
 205 aa
22.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.