Expression of NCEH1 in cancer - Summary

CANCER ATLAS

Gene description

Neutral cholesterol ester hydrolase 1

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA026888

GENE INFORMATION
Gene name	NCEH1 (HGNC Symbol)
Synonyms	AADACL1, KIAA1363, NCEH
Description	Neutral cholesterol ester hydrolase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q26.31
Chromosome location (bp)	172630249 - 172711218
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000144959 (version 83.38)
Entrez gene	57552
UniProt	Q6PIU2 (UniProt - Evidence at protein level)
neXtProt	NX_Q6PIU2
Antibodypedia	NCEH1 antibodies

PROTEIN BROWSER

NCEH1-001	NCEH1-002	NCEH1-201	NCEH1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NCEH1-001 ENSP00000418571 ENST00000475381		MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016787 [hydrolase activity] GO:0052689 [carboxylic ester hydrolase activity] Show all	440 aa 49.1 kDa	No	0
NCEH1-002 ENSP00000392934 ENST00000424772	H7C046 [Direct mapping] Neutral cholesterol ester hydrolase 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016787 [hydrolase activity] Show all	307 aa 33.9 kDa	No	1
NCEH1-201 ENSP00000442464 ENST00000538775	A0A0A0MTJ9 [Direct mapping] Neutral cholesterol ester hydrolase 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006470 [protein dephosphorylation] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016787 [hydrolase activity] GO:0017171 [serine hydrolase activity] GO:0042301 [phosphate ion binding] GO:0052689 [carboxylic ester hydrolase activity] GO:0060395 [SMAD protein signal transduction] Show all	448 aa 49.9 kDa	No	1
NCEH1-202 ENSP00000443227 ENST00000543711	Q6PIU2 [Direct mapping] Neutral cholesterol ester hydrolase 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005783 [endoplasmic reticulum] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016042 [lipid catabolic process] GO:0016787 [hydrolase activity] GO:0052689 [carboxylic ester hydrolase activity] Show all	275 aa 31.2 kDa	No	0