Fields »
ABOUT
HELP
BLOG
GLRA3

GENERAL INFORMATION

Gene name

 GLRA3

Gene description

 Glycine receptor, alpha 3

Protein class

 FDA approved drug targets
Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (cerebral cortex, breast)
GTEx:Tissue enhanced (hypothalamus, cerebral cortex)
FANTOM5:Tissue enhanced (pituitary gland, brain)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebral cortex, breast)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (hypothalamus, cerebral cortex)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (pituitary gland, brain)

GENE INFORMATION

Gene name

 GLRA3

Synonyms

Description

 Glycine receptor, alpha 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the glycine receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Chromosome

 4

Cytoband

 q34.1

Chromosome location (bp)

 174636914 - 174829314

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000145451 (version 83.38)

Entrez gene

 8001

UniProt

 O75311 (UniProt - Evidence at protein level)

neXtProt

 NX_O75311

Antibodypedia

 GLRA3 antibodies

PROTEIN BROWSER
GLRA3-001
GLRA3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GLRA3-001
ENSP00000274093
ENST00000274093
O75311 [Direct mapping]
Glycine receptor subunit alpha-3
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
FDA approved drug targets
   Small molecule drugs
Show all
GO:0005230 [extracellular ligand-gated ion channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006810 [transport]
GO:0006811 [ion transport]
GO:0007218 [neuropeptide signaling pathway]
GO:0009897 [external side of plasma membrane]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016594 [glycine binding]
GO:0016934 [extracellular-glycine-gated chloride channel activity]
GO:0022824 [transmitter-gated ion channel activity]
GO:0030054 [cell junction]
GO:0034220 [ion transmembrane transport]
GO:0034707 [chloride channel complex]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043113 [receptor clustering]
GO:0043200 [response to amino acid]
GO:0043679 [axon terminus]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0050877 [neurological system process]
GO:0055085 [transmembrane transport]
GO:0060012 [synaptic transmission, glycinergic]
GO:0072578 [neurotransmitter-gated ion channel clustering]
GO:0097112 [gamma-aminobutyric acid receptor clustering]
GO:1902476 [chloride transmembrane transport]
Show all
 464 aa
53.8 kDa 		Yes 4
GLRA3-002
ENSP00000345284
ENST00000340217
O75311 [Direct mapping]
Glycine receptor subunit alpha-3
Show all
Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
FDA approved drug targets
   Small molecule drugs
Show all
GO:0005230 [extracellular ligand-gated ion channel activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006810 [transport]
GO:0006811 [ion transport]
GO:0007218 [neuropeptide signaling pathway]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016594 [glycine binding]
GO:0016934 [extracellular-glycine-gated chloride channel activity]
GO:0022824 [transmitter-gated ion channel activity]
GO:0030054 [cell junction]
GO:0034220 [ion transmembrane transport]
GO:0034707 [chloride channel complex]
GO:0042391 [regulation of membrane potential]
GO:0043005 [neuron projection]
GO:0043200 [response to amino acid]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0050877 [neurological system process]
GO:0055085 [transmembrane transport]
GO:0060012 [synaptic transmission, glycinergic]
GO:1902476 [chloride transmembrane transport]
Show all
 449 aa
52 kDa 		Yes 4

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.