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Weak to moderate cytoplasmic and/or nuclear immunoreactivity was observed in prostate cancers, several hepatocellular carcinomas and a few thyroid and gastric cancers. Remaining cancer cells were mainly negative.
GENE INFORMATION
Gene name
LHFPL2 (HGNC Symbol)
Synonyms
KIAA0206
Description
Lipoma HMGIC fusion partner-like 2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
